Posts Tagged ‘hippocampus’

Benefits Of Acetyl L-Carnitine Supplements

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Acetyl-L-carnitine (ALC) is a synthetic, acetylated version of the nat­urally occurring nitrogenous substance L-carnitine. This is a sub­stance that enhances oxidative phosphorylation (ATP production in the mitochondria) by supplying the mitochondria with certain fatty acids it needs.

Taking oral L-carnitine does not greatly increase the supply of carnitine to the brain cells (although it does to nonbrain cells) since it does not readily cross the blood-brain barrier; but by sticking an acetyl group on the L-carnitine molecule and forming ALC, we can cross this barrier and thus supply the brain with extra L-carnitine.

 

Animal studies have shown ALC prevents age-related lipid per­oxidation of brain cells and age-associated reduction in nerve growth factor, a critical substance for maintaining normal function­ing in the mammalian brain. Other studies show that ALC shields the brain from age-induced damage, including protecting NMDA receptors in the hippocampus against damage by free radicals.

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